The Peroxiredoxin-4 Rabbit Monoclonal Antibody (CAB9131) is a valuable tool for researchers studying Peroxiredoxin-4, a vital antioxidant enzyme involved in redox regulation within cells. This antibody, derived from rabbit monoclonal sources, demonstrates high specificity and sensitivity when detecting Peroxiredoxin-4 in human samples through techniques such as Western blotting.Peroxiredoxin-4 is known for its role in protecting cells from oxidative stress and maintaining cellular homeostasis. Its function in regulating redox signaling pathways has garnered interest in its implications for various diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions.
By targeting Peroxiredoxin-4 with this antibody, researchers can gain insight into its expression levels and activity in different cell types, advancing our understanding of its contributions to health and disease.Overall, the Peroxiredoxin-4 Rabbit Monoclonal Antibody (CAB9131) provides a reliable tool for investigating Peroxiredoxin-4 biology and its potential as a therapeutic target in diseases characterized by oxidative stress and redox dysregulation. Its specificity and performance in detecting Peroxiredoxin-4 make it a valuable asset for studies in molecular biology, biochemistry, and biomedical research.
The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
Purification Method:
Affinity purification
Gene ID:
10549
Clone Number:
ARC1442
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Peroxiredoxin 4 (PRDX4) (PRDX4) Rabbit mAb (CAB9131) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
