null

Peroxiredoxin 2 (PRDX2) Polyclonal Antibody (CAB21814)

SKU:
CAB21814
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
IF
€129 - €359
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Peroxiredoxin 2 (PRDX2) Polyclonal Antibody
SKU:CAB21814
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human Peroxiredoxin 2 (PRDX2) (NP_859428.1).
Sequence:MASG NARI GKPA PDFK ATAV VDGA FKEV KLSD YKGK YVVL FFYP LDFT FVCP TEII AFSN RAED FRKL GCEV LGVS VDSQ FTHL AWYE QGPK REVA AKLT PSGP SSVA SWPL LNLW NLRF PIVK IMET LPPK SLRM MTVI SI
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:PRP; TSA; PRX2; PTX1; TPX1; NKEFB; PRXII; TDPX1; NKEF-B; HEL-S-2a; Peroxiredoxin 2 (PRDX2)
Positive Sample:Hep G2,Mouse brain,Rat brain,Rat spleen,Rat heart
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:22kDa
Observed MW:Refer to figures

This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.

Purification Method:Affinity purification
Gene ID:7001
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Peroxiredoxin 2 (PRDX2) Rabbit pAb (CAB21814) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

Related Products