The Perilipin A Rabbit Monoclonal Antibody (CAB4758) is a valuable tool for researchers studying Perilipin A, a protein involved in lipid metabolism and storage within adipocytes. This antibody, developed using rabbit monoclonal technology, demonstrates high specificity and sensitivity for detecting Perilipin A in human samples.Perilipin A plays a crucial role in regulating lipid droplet formation and breakdown, making it an important target for studying obesity, metabolic disorders, and related conditions. By utilizing the CAB4758 antibody in techniques such as immunofluorescence and immunohistochemistry, researchers can gain insights into the localization and expression levels of Perilipin A in various tissues and cell types.
Furthermore, understanding the function and regulation of Perilipin A can provide valuable information for developing therapeutic strategies aimed at targeting lipid metabolism-related diseases. The CAB4758 antibody offers researchers a reliable tool for advancing their research in the fields of metabolism, obesity, and lipid biology.
Product Name:
Perilipin A Rabbit Monoclonal Antibody
SKU:
CAB4758
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 400-500 of human Perilipin A (O60240).
Sequence:
HYVP LPRL SLME PESE FRDI DNPP AEVE RREA ERRA SGAP SAGP EPAP RLAQ PRRS LRSA QSPG APPG PGLE DEVA TPAA PRPG FPAV PREK PKRR VSDS F
The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5346
Clone Number:
ARC1122
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Perilipin A Rabbit mAb (CAB4758) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
