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PerCP/Cyanine5.5 Anti-Rat CD45 Antibody [OX-1] (AGEL2448)

SKU:
AGEL2448
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Rat
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
OX-1
Conjugation:
PerCP/Cyanine5.5
€169 - €409
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Rat CD45 Antibody [OX-1]

The PerCP-Cyanine5.5 Anti-Rat CD45 Antibody (clone OX-1) is a vital tool for researchers exploring immune cell populations and hematopoiesis in rat models. This monoclonal antibody, specifically designed to target CD45, a classic marker for hematopoietic cells, offers high specificity and sensitivity in flow cytometry applications. With its PerCP-Cyanine5.5 conjugation, this antibody allows for multicolor flow cytometry experiments, enabling simultaneous detection of multiple cell populations. The OX-1 clone is well-characterized and validated for its performance in rat samples, ensuring reliable and reproducible results in experimental settings.

CD45, also known as leukocyte common antigen, is essential for signal transduction in immune cells and plays a crucial role in cell activation and differentiation. By targeting CD45, researchers can gain valuable insights into immune cell development, function, and activation states, making this antibody a valuable asset for studies in immunology, transplantation, and infectious diseases.Overall, the PerCP-Cyanine5.5 Anti-Rat CD45 Antibody (clone OX-1) offers a powerful tool for investigating rat immune cell subsets and understanding the complexities of immune responses in various experimental contexts.

Product Title:PerCP/Cyanine5.5 Anti-Rat CD45 Antibody [OX-1]
SKU:AGEL2448
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-1
Synonyms:Receptor-type tyrosine-protein phosphatase C;Leukocyte common antigen; LCA; T200; Ly-5;Ptprc;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P04157
Gene ID:19265
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

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