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PerCP/Cyanine5.5 Anti-Rat CD44H Antibody [OX-49] (AGEL2430)

SKU:
AGEL2430
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Rat
Host Species:
Mouse
Isotype:
Mouse IgG2a, κ
Clone:
OX-49
Conjugation:
PerCP/Cyanine5.5
€169 - €409

Description

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PerCP/Cyanine5.5 Anti-Rat CD44H Antibody [OX-49]

The PERCP-Cyanine5.5 Anti-Rat CD44H Antibody (OX-49) - AGEL2430The PERCP-Cyanine5.5 Anti-Rat CD44H Antibody (OX-49) - AGEL2430 is a crucial tool for researchers studying rat CD44H, a cell surface glycoprotein associated with cellular adhesion and migration processes. This antibody, specifically developed for rat samples, is highly sensitive and validated for use in flow cytometry applications. It specifically binds to the CD44H protein, allowing for precise detection and analysis in various cell types, making it an excellent choice for investigations in immunology, cell biology, and cancer research.

CD44H, a variant of the CD44 molecule, is known for its involvement in cell-cell interactions and signaling pathways that influence cell behavior and function. Its role in processes like inflammation, tissue repair, and tumor metastasis highlights its relevance in various physiological and pathological conditions. Researchers can utilize this antibody to explore the functions and mechanisms associated with CD44H, gaining insights that could lead to advancements in therapeutic strategies for cancer and other diseases where CD44H plays a significant role.

Product Title:PerCP/Cyanine5.5 Anti-Rat CD44H Antibody [OX-49]
SKU:AGEL2430
Size:50 Tests, 100 Tests, 200 Tests
Clone No:OX-49
Synonyms:Pgp-1; H-CAM; CD44s;CD44H;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P26051
Gene ID:12505
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is an 80-95 kD cell surface glycoprotein. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. It is up-regulated when T cells and B cells are activated. It was reported that CD44 is a valuable marker for memory T cells. CD44 is an adhesion molecule involved in leukocyte adhesion and homing to lymphoid organs. The OX-49 antibody reacts with CD44H (known as CD44s) expressed on most leukocytes, except for a subset of B lymphocytes. The epitope recognized by OX-49 antibody has been mapped to a region on both the standard, CD44s, and the splice variant, CD44v, isoforms of CD44. However it was reported that OX-49 antibody cannot detect the CD44V isoform, possibly due to conformational changes in the epitope.

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