The PerCP-Cyanine5.5 Anti-Rat CD3 Antibody (G4.18) (AGEL2461) is a powerful tool for researchers studying the immune system of rats. This antibody specifically targets the CD3 protein, a key component of the T-cell receptor complex involved in immune responses. The PerCP and Cyanine5.5 fluorophores provide excellent sensitivity and resolution for flow cytometry experiments, allowing for precise identification and analysis of CD3-expressing cells.The AGEL2461 antibody is meticulously validated for use in flow cytometry applications, ensuring reliable and reproducible results. It is designed to be highly specific, enabling researchers to confidently distinguish CD3-positive cells in complex cell populations.
By utilizing this antibody, researchers can delve deeper into the functioning of rat T cells, investigate immune responses, and explore potential therapeutic targets for various diseases.The CD3 protein plays a crucial role in T cell activation and function, making the PerCP-Cyanine5.5 Anti-Rat CD3 Antibody (G4.18) (AGEL2461) an essential tool for immunology research. Whether studying T cell development, immune responses, or immune-mediated diseases in rats, this antibody provides a valuable resource for researchers seeking to expand their understanding of T cell biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P19377 Q64159 D4A5M2
Gene ID:
25710,300678,315609,25300
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3 is a complex composed of δ, γ, ε, and ζ chains. They are 20-25 kD members of the immunoglobulin superfamily and associated with the T cell receptor (TCR). CD3 is expressed on thymocytes, peripheral T cells, some NK-T cells, and dendritic epidermal T cells. CD3 is involved in antigen recognition, signal transduction, and T cell activation.