The Rat CD3 Antibody (G4.18) is a potent tool designed for researchers studying immune responses in rats. This polyclonal antibody is specifically engineered to detect and bind to CD3, a crucial cell surface marker found on T cells, B cells, and natural killer cells in the immune system. With its high reactivity and specificity towards rat samples, this antibody is essential for various immunology studies, including T cell activation, immune cell profiling, and antigen recognition.CD3, a key signaling component of the T cell receptor complex, plays a pivotal role in T cell activation and function. By targeting CD3, researchers can gain insights into T cell development, maturation, and effector functions.
The Rat CD3 Antibody (G4.18) is an invaluable tool for exploring the dynamics of T cell-mediated immune responses in rat models, enabling researchers to delve deeper into the mechanisms underlying immune regulation and host defense.With its versatile applications in immunology research, the Rat CD3 Antibody (G4.18) opens up possibilities for investigating various aspects of cellular immunity and immune system function in rat models. Whether studying immune responses in infection, inflammation, or autoimmune diseases, this antibody provides a reliable and specific tool for unraveling the complexities of the rat immune system and advancing our understanding of immunological processes.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P19377 Q64159 D4A5M2
Gene ID:
25710,300678,315609,25300
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3 is a complex composed of δ, γ, ε, and ζ chains. They are 20-25 kD members of the immunoglobulin superfamily and associated with the T cell receptor (TCR). CD3 is expressed on thymocytes, peripheral T cells, some NK-T cells, and dendritic epidermal T cells. CD3 is involved in antigen recognition, signal transduction, and T cell activation.