The PERCP-Cyanine5.5 Anti-Mouse LY-6G/LY-6C (GR-1) Antibody (RB6-8C5) is a vital tool for researchers studying mouse immune cells and inflammation. This antibody, optimized for flow cytometry applications, specifically targets the LY-6G and LY-6C antigens found on myeloid cells such as neutrophils and inflammatory monocytes. By utilizing this antibody, researchers can accurately identify and analyze these cell populations in biological samples, enabling a deeper understanding of immune responses and inflammatory processes in various experimental models.LY-6G and LY-6C are cell surface markers that play essential roles in immune cell activation and trafficking during immune responses.
The RB6-8C5 antibody provides high specificity and sensitivity for detecting these markers, allowing for precise characterization of different myeloid cell subsets in mice. This information is crucial for investigating immune mechanisms in diseases such as infection, inflammation, and cancer, where myeloid cells are key players in the tissue microenvironment.With its reliable performance and validated compatibility with flow cytometry techniques, the PERCP-Cyanine5.5 Anti-Mouse LY-6G/LY-6C (GR-1) Antibody (RB6-8C5) is a valuable asset for researchers seeking to unravel the complexities of the immune system and its involvement in disease pathogenesis.
PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35461 P0CW03
Gene ID:
546644 ,17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Gr-1 is a 21-25 kD protein also known as Ly-6G/Ly-6C. This myeloid differentiation antigen is a glycosylphosphatidylinositol (GPI)-linked protein expressed on granulocytes and macrophages. In bone marrow, the expression levels of Gr-1 directly correlate with granulocyte differentiation and maturation; Gr-1 is also transiently expressed on bone marrow cells in the monocyte lineage. Immature Myeloid Gr-1+ cells play a role in the development of antitumor immunity.