The PerCP-Cyanine5.5 Anti-Mouse CD45 Antibody (104-2) offered by Assay Genie is a high-quality tool designed for researchers working with mouse samples and studying the CD45 protein, a key marker for immune cells. This antibody is optimized for flow cytometry applications, allowing for precise identification and analysis of immune cell populations in various experimental settings.CD45, a transmembrane protein found on all nucleated hematopoietic cells, is essential for immune cell activation and signaling. The PerCP-Cyanine5.5 Anti-Mouse CD45 Antibody (104-2) specifically targets the mouse CD45 antigen, enabling researchers to distinguish between different immune cell subsets based on their expression levels of this protein.
With its high specificity and sensitivity, this antibody is a valuable tool for immunology research, including studies focused on immune cell development, function, and regulation.By using the PerCP-Cyanine5.5 Anti-Mouse CD45 Antibody (104-2) in flow cytometry experiments, researchers can gain valuable insights into the dynamics of immune cell populations in various biological systems. Its reliability and consistent performance make it an indispensable reagent for investigating the complex interplay of immune cells in health and disease, including infection, inflammation, and immune-related disorders. Trust Assay Genie for high-quality antibodies that drive groundbreaking research in immunology and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Gene ID:
19264
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.