The PERCP-Cyanine5.5 Anti-Mouse CD335 Antibody (29A1.4) is a key tool for immunology research, specifically targeting the CD335 protein, also known as NKp46. This antibody, validated for flow cytometry applications, is highly specific for mouse samples and enables precise detection and analysis of CD335 expression in various immune cell populations.CD335, a natural cytotoxicity receptor expressed on natural killer (NK) cells and some T cell subsets, plays a vital role in the recognition and elimination of target cells, particularly in the context of viral infections and tumor surveillance. Understanding the expression and function of CD335 is essential for unraveling the mechanisms of immune response against pathogens and cancer cells.
Utilizing the PERCP-Cyanine5.5 Anti-Mouse CD335 Antibody (29A1.4) in your research can provide valuable insights into the activity of NK cells and their role in immune surveillance and anti-tumor immunity. By accurately detecting and quantifying CD335 expression, this antibody supports the investigation of NK cell biology and the development of novel immunotherapies targeting NK cell function.Get reliable and specific detection of CD335 in mouse samples with the PERCP-Cyanine5.5 Anti-Mouse CD335 Antibody (29A1.4) and enhance your research in immunology, cancer biology, and infectious diseases.
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q8C567
Gene ID:
17086
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.