The PerCP-Cyanine5.5 Anti-Mouse CD335 Antibody (29A1.4) from Assay Genie is a powerful tool for studying natural killer cells in mouse models. This antibody specifically targets CD335, also known as NKp46, a key marker for natural killer cells. By binding to CD335, this antibody allows for the visualization and analysis of natural killer cells in various tissues and experimental conditions.NK cells are a critical component of the immune system, playing a key role in the recognition and elimination of infected or abnormal cells. The ability to accurately identify and study these cells is essential for understanding immune responses, infectious diseases, and cancer immunology.
The PerCP-Cyanine5.5 Anti-Mouse CD335 Antibody is validated for use in flow cytometry applications, offering precise and reliable detection of CD335-expressing cells in mouse samples.Researchers in immunology, oncology, and infectious disease fields will find this antibody invaluable for investigating the function and behavior of natural killer cells in experimental settings. With its high specificity and sensitivity, the PerCP-Cyanine5.5 Anti-Mouse CD335 Antibody (29A1.4) provides a valuable tool for advancing our understanding of immune responses and developing targeted therapies for various diseases.
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q8C567
Gene ID:
17086
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.