The PerCP-Cyanine5.5 Anti-Human CD54 Antibody (15.2), available at www.assaygenie.com, is a potent tool for detecting and analyzing CD54, a crucial cell surface protein involved in immune responses and cell adhesion. This monoclonal antibody, engineered to specifically target human CD54, is ideal for use in various immunological studies and research applications.CD54, also known as intercellular adhesion molecule-1 (ICAM-1), plays a pivotal role in mediating interactions between immune cells and facilitating inflammatory responses. It is a key player in immune cell adhesion and migration processes, making it a significant target for exploring immune system function in health and disease.
The PerCP-Cyanine5.5 Anti-Human CD54 Antibody (15.2) provides researchers with a reliable tool to study CD54 expression and localization in different cell types and experimental settings.This antibody is meticulously validated for its specificity and sensitivity in detecting human CD54, ensuring accurate and reproducible results in flow cytometry, immunofluorescence, and other experimental techniques. By utilizing the PerCP-Cyanine5.5 Anti-Human CD54 Antibody (15.2), researchers can deepen their understanding of CD54's role in immune responses, inflammation, and immune cell interactions, paving the way for advancements in immunology research and potential therapeutic developments.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05362
Gene ID:
3383
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells, high endothelial venules, T and B cells, monocytes/macrophages, granulocytes, and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1), CD11b/CD18 (Mac-1), CD11c/CD18 (p150, 95) as well as hyaluronan and fibrinogen.