The PERCP-Cyanine5.5 Anti-Human CD48 Antibody (156-4H9) available on www.assaygenie.com is a crucial tool for researchers studying immune responses and cell interactions in humans. This antibody, specifically targeting the CD48 protein on cell surfaces, is highly specific and exhibits strong reactivity with human samples. Validated for use in various applications, including flow cytometry and immunofluorescence, it enables precise detection and analysis of CD48 expression in different cell types.CD48, a key molecular marker involved in immune signaling and cell communication, plays a vital role in modulating immune responses and regulating immune cell functions. By targeting CD48, researchers can gain valuable insights into the mechanisms underlying immune system activation, cell adhesion, and signaling pathways crucial for immune surveillance and response.
The detailed analysis facilitated by this antibody is instrumental for unraveling the complexities of immune regulation and understanding its implications in health and disease.Suitable for a wide range of research areas, including immunology, oncology, and autoimmune disorders, the PERCP-Cyanine5.5 Anti-Human CD48 Antibody (156-4H9) opens up new possibilities for uncovering the role of CD48 in various physiological and pathological conditions. Its high specificity and sensitivity make it an indispensable tool for scientists striving to decipher the intricate workings of the human immune system and develop targeted therapies for immune-related diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P09326
Gene ID:
962
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD48 is a 40-47 kD GPI-anchored membrane protein, also known as Blast-1 and HuLy-m3. It is a member of the CD2 family that contains 2 IgSF domains and is widely expressed on both resting and activated hematopoietic cells with the exception of granulocytes, platelets, and erythrocytes. CD48 binds to CD2 at a considerably (>100-fold) lower affinity than CD58. It is thought to contribute to T cell activation. The cytoplasmic tail of CD48 has been shown to bind to the kinases Lck and Fyn.