The PERCP/Cyanine5.5 Anti-Human CD44 Antibody (Hermes-1) offered by AssayGenie (www.assaygenie.com/percp-cyanine5-5-anti-human-cd44-antibody-hermes-1/) is a cutting-edge tool designed for researchers in the field of immunology and oncology. This antibody is developed to specifically target CD44, a cell surface receptor prominently involved in cell adhesion, migration, and signaling processes. The antibody is optimized for use with human samples and is validated for precise detection and analysis through flow cytometry and other fluorescent-based applications.CD44, a multifunctional glycoprotein, is known to play crucial roles in various physiological and pathological processes, including cancer metastasis, immune response modulation, and inflammation.
The Hermes-1 antibody enables researchers to investigate the expression and localization of CD44 in different cell types, offering insights into its involvement in diseases like cancer and inflammatory disorders. By targeting CD44, researchers can delve deeper into understanding its function and potential therapeutic implications in diseases where CD44 dysregulation occurs.In summary, the PERCP/Cyanine5.5 Anti-Human CD44 Antibody (Hermes-1) from AssayGenie provides a high-quality solution for researchers aiming to explore the intricate roles of CD44 in health and disease. Its specificity and reliability make it an invaluable tool for advancing research in the fields of immunology and oncology.
PerCP/Cyanine5.5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16070
Gene ID:
960
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from a low or mid level of intensity to high expression levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.