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PerCP/Cyanine5.5 Anti-Human CD40 Antibody [3A8] (AGEL2796)

SKU:
AGEL2796
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG2a, κ
Clone:
3A8
Conjugation:
PerCP/Cyanine5.5
€239 - €829
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Human CD40 Antibody [3A8]

The PERCP-cyanine5.5 Anti-Human CD40 Antibody (3A8) offered by Assay Genie is a highly specific and reliable tool for researchers studying CD40, a key cell surface receptor involved in immune responses and antigen presentation. This antibody, optimized for use in flow cytometry applications, is designed to target human CD40 molecules with high affinity and sensitivity.CD40, a member of the tumor necrosis factor receptor superfamily, plays a crucial role in regulating immune responses by mediating interactions between antigen-presenting cells and T cells. Its involvement in immune activation, B cell proliferation, and cytokine production makes it a pivotal target for investigating pathways related to autoimmune diseases, infectious conditions, and cancer immunotherapy.

By utilizing the PERCP-cyanine5.5 Anti-Human CD40 Antibody (3A8), researchers can accurately detect and quantify CD40 expression on various cell types, providing valuable insights into immune system functioning and potential therapeutic targets. With its validated performance and specificity for human CD40, this antibody is a valuable asset for studies in immunology, oncology, and vaccine development.

Product Title:PerCP/Cyanine5.5 Anti-Human CD40 Antibody [3A8]
SKU:AGEL2796
Size:20 Tests, 100 Tests, 200 Tests
Clone No:3A8
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2a, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P25942
Gene ID:958
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The 5C3 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA, partially blocking CD40 binding to CD40L, and B cells rescue from apoptosis.

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