The PERCP-Cyanine5.5 Anti-Human CD31 Antibody (158-2B3) offered by AssayGenie is a highly specific reagent designed for the detection of CD31, a cell surface glycoprotein also known as Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1). This monoclonal antibody, suitable for use in flow cytometry applications, is particularly responsive in human samples and has been extensively validated for reliable performance.CD31 is a well-established marker of endothelial cells and plays a crucial role in various physiological and pathological processes, including angiogenesis, inflammation, and vascular integrity. By targeting CD31 with this antibody, researchers can accurately identify and analyze endothelial cells, investigate angiogenic processes, and explore the involvement of CD31 in diseases such as cancer, cardiovascular disorders, and inflammatory conditions.
With its high specificity and sensitivity, the PERCP-Cyanine5.5 Anti-Human CD31 Antibody (158-2B3) from AssayGenie provides a valuable tool for advancing research in vascular biology, immunology, and oncology. Researchers can confidently rely on this antibody to facilitate precise detection and characterization of CD31-expressing cells in their studies, helping to deepen the understanding of endothelial cell biology and its implications in various disease contexts.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P16284
Gene ID:
5175
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD31 is a 130-140 kD type I transmembrane glycoprotein also known as platelet endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. It is expressed on monocytes, platelets, granulocytes, endothelial cells and lymphocyte subsets. CD31 has been reported to bind CD38 and be involved in wound healing, angiogenesis, and cellular migration in an inflammatory situation.