The PerCP-Cyanine5.5 Anti-Human CD3 Antibody (UCHT1) offered by AssayGenie is a vital tool for immunology research focused on studying human CD3 expression. This monoclonal antibody is specifically designed for flow cytometry applications, providing researchers with a precise method to analyze and quantify CD3-positive cells in various biological samples.With its high specificity and sensitivity towards human CD3, the UCHT1 antibody facilitates the identification and characterization of T cells in human immune responses. By targeting the CD3 antigen, an essential component of the T cell receptor complex, this antibody enables detailed investigations into T cell activation, differentiation, and function.
The UCHT1 antibody's compatibility with PerCP-Cyanine5.5 allows for multiplexing with other fluorophores, enhancing the versatility of flow cytometry experiments. Its reliable performance and reproducibility make it an indispensable tool for research areas such as immunophenotyping, immune monitoring, and studies on T cell-mediated diseases.Researchers exploring T cell biology, immunotherapy, autoimmune disorders, and infectious diseases will find the PerCP-Cyanine5.5 Anti-Human CD3 Antibody (UCHT1) from AssayGenie to be a valuable asset in their quest for deeper insights into human immune responses.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P07766
Gene ID:
915
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.