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PerCP/Cyanine5.5 Anti-Human CD22 Antibody [BU59]

SKU:
AGEL2821
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, κ
Clone:
BU59
Conjugation:
PerCP/Cyanine5.5
€209 - €709
Frequently bought together:

Description

PerCP/Cyanine5.5 Anti-Human CD22 Antibody [BU59]

The PERCP-Cyanine5.5 Anti-Human CD22 Antibody (BU59) offered by Assay Genie is a cutting-edge tool designed for researchers delving into the intricacies of the CD22 cell surface protein. This antibody, optimized for use in flow cytometry, is tailored for high reactivity with human samples, ensuring accurate and reliable results in a variety of experimental settings.CD22, a key player in immune cell regulation and B-cell signaling, has been identified as a promising target for studies related to immunology, cancer research, and autoimmune disorders. By specifically binding to the CD22 protein, the PERCP-Cyanine5.5 Anti-Human CD22 Antibody (BU59) facilitates precise detection and analysis of CD22 expression in diverse cell types, offering researchers valuable insights into the role of CD22 in health and disease.

Researchers seeking to unravel the complexities of immune regulation, B-cell biology, and antibody-targeted therapies will benefit from the exceptional specificity and sensitivity of this antibody. With its proven efficacy in flow cytometry applications, the PERCP-Cyanine5.5 Anti-Human CD22 Antibody (BU59) from Assay Genie is a valuable asset for advancing scientific understanding in the fields of immunology and oncology.

Product Name:PerCP/Cyanine5.5 Anti-Human CD22 Antibody [BU59]
Product Code:AGEL2821
Clone No:BU59
Synonyms:B-cell receptor CD22,Cd22,B-lymphocyte cell adhesion molecule,BL-CAM,Sialic acid-binding Ig-like lectin 2,Siglec-2,T-cell surface antigen Leu-14,CD22,Lyb-8, Siglec2
Reactivity:Human
Host Species:Mouse
Applications:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control [MOPC-21] (AGEL2555)
Conjugation:PerCP/Cyanine5.5
Form:Liquid
Fluorescent Label:PerCP/Cyanine5.5 is designed to be excited by the blue laser (488 nm) and detected using an optical filter centered near 675 nm (e.g., a 690/50 nm bandpass filter).
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Swissprot:P20273
Stability & Storage:Keep as concentrated solution. Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.

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