The PerCP-Cyanine5.5 Anti-Human CD20 Antibody (BCA-B20) available at AssayGenie is a high-quality research tool designed for the detection and analysis of the CD20 protein, a cell surface marker found on B cells. This antibody is specifically engineered for use in flow cytometry applications and is optimized for binding to human CD20, allowing for precise identification and characterization of B cells in various samples.CD20 is a crucial marker for B cell identification and is commonly used in research related to immunology, oncology, and autoimmune diseases. The PerCP-Cyanine5.5 Anti-Human CD20 Antibody offers reliable and sensitive detection of CD20, making it a valuable tool for studying B cell populations in diverse research settings.
Its accuracy and specificity make it ideal for experiments aimed at understanding B cell biology, investigating immune responses, or exploring therapeutic interventions targeting B cell-mediated disorders.By utilizing the PerCP-Cyanine5.5 Anti-Human CD20 Antibody from AssayGenie, researchers can effectively study the role of CD20 in health and disease, paving the way for advancements in personalized medicine, immunotherapy, and targeted treatments for conditions involving B cell dysregulation. Trust in the quality and performance of this antibody to enhance your research outcomes and deepen your understanding of CD20 biology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P11836
Gene ID:
931
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.