The PerCP-Cyanine5.5 Anti-Human CD1a Antibody (OKT-6) available at assaygenie.com is a valuable tool for researchers studying immune responses and cell surface molecules. This antibody, specifically designed for detecting human CD1a, a marker present on antigen-presenting cells like dendritic cells, offers high reactivity and specificity.CD1a is essential for presenting lipid antigens to T cells, contributing to immune system activation and regulation. The OKT-6 antibody, validated for use in flow cytometry and fluorescence microscopy, binds specifically to CD1a, allowing for precise detection and analysis of CD1a-expressing cells in various experimental settings.
For immunologists, cancer researchers, and others interested in cell-mediated immunity and antigen presentation, the PerCP-Cyanine5.5 Anti-Human CD1a Antibody (OKT-6) provides a reliable tool for investigating the role of CD1a in immune responses and diseases. Its versatility and performance make it a valuable asset in advancing our understanding of immune system function and disease pathology.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P06126
Gene ID:
909
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.