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PerCP Anti-Mouse CD49b Antibody [DX5] (AGEL3257)

SKU:
AGEL3257
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgM, k
Clone:
DX5
Conjugation:
PerCP
$239 - $551
Frequently bought together:

Description

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PerCP Anti-Mouse CD49b Antibody [DX5]

The PERCP Anti-Mouse CD49b Antibody (DX5) is a specialized tool designed for the detection and analysis of CD49b, a cell surface marker crucial in immune cell interactions and migration. This antibody, raised in mice, exhibits high specificity and sensitivity when used in flow cytometry applications, allowing for precise identification and characterization of CD49b-expressing cells in mouse samples.CD49b, also known as DX5, serves as a marker for natural killer cells and a subset of T cells, playing a key role in their function and activation. By targeting CD49b with this antibody, researchers can study the behavior and distribution of these immune cell populations in various experimental settings, providing valuable insights into immune responses, inflammation, and host defense mechanisms.

The versatile PERCP Anti-Mouse CD49b Antibody (DX5) is an essential addition to immunology research, facilitating the investigation of immune cell dynamics and the impact of CD49b expression in physiological and pathological conditions. Its reliable performance and compatibility with flow cytometry make it a valuable tool for studies focusing on immune cell subsets, immunotherapy, and the development of novel treatment strategies for immune-related disorders.

Product Title:PerCP Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL3257
Size:25µg, 100µg
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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