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PerCP Anti-Mouse CD49b Antibody [DX5] (AGEL3255)

SKU:
AGEL3255
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgM, k
Clone:
DX5
Conjugation:
PerCP
$191 - $467
Frequently bought together:

Description

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PerCP Anti-Mouse CD49b Antibody [DX5]

The DX5 anti-mouse CD49b Antibody (AGEL3255) is a powerful tool for researchers studying immune cell populations within the mouse model system. This monoclonal antibody specifically targets CD49b, a surface marker found on natural killer (NK) cells and a subset of T cells. By utilizing this antibody, researchers can effectively identify and isolate CD49b-positive cells for further analysis, whether for flow cytometry, immunohistochemistry, or other research applications.CD49b, also known as DX5, is a key molecule involved in the function and regulation of NK cells, which play a crucial role in the body's immune response against infected or cancerous cells. The ability to accurately detect and quantify CD49b expression is essential for understanding the role of NK cells in immunity, inflammation, and disease progression.

Researchers can rely on the DX5 anti-mouse CD49b Antibody (AGEL3255) for its specificity, sensitivity, and reproducibility in experimental settings.With its high reactivity and validation for mouse samples, this antibody is a valuable resource for studies in immunology, cancer research, and beyond. By targeting CD49b with precision, researchers can gain deeper insights into the functions and behavior of NK cells, paving the way for advancements in therapeutic strategies against infections, tumors, and other immune-related conditions.

Product Title:PerCP Anti-Mouse CD49b Antibody [DX5]
SKU:AGEL3255
Size:50 Tests, 100 Tests, 200 Tests
Clone No:DX5
Synonyms:Integrin alpha-2;CD49 antigen-like family member B;Collagen receptor;Platelet membrane glycoprotein Ia;GPIa;VLA-2 subunit alpha;CD49b;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgM, κ
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62469
Gene ID:16398
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

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