The Mouse CD11c Monoclonal Antibody (N418) is a powerful tool for researchers studying the immune system and dendritic cells. This antibody, manufactured by Assay Genie, specifically targets the CD11c protein, a key marker for dendritic cells involved in antigen presentation and immune response regulation.The N418 antibody is optimized for use in flow cytometry, immunofluorescence, and immunohistochemistry applications, providing reliable and consistent results in experimental settings. Its high specificity for the CD11c protein allows for precise detection and analysis of dendritic cells in various research models.Dendritic cells are essential for initiating and regulating immune responses, making the CD11c antibody a valuable asset for studies related to immunology, infectious diseases, and autoimmune disorders.
By targeting CD11c, researchers can gain insights into dendritic cell function and immune system dynamics, paving the way for advancements in vaccine development, immunotherapy, and disease diagnostics.In summary, the Mouse CD11c Monoclonal Antibody (N418) from Assay Genie offers researchers a reliable tool for studying dendritic cells and immune response mechanisms, facilitating discoveries in immunology research and therapeutic development.
Product Title:
PerCP Anti-Mouse CD11c Antibody [N418]
SKU:
AGEL3171
Size:
25µg, 100µg
Clone No:
N418
Synonyms:
Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Form:
Liquid
Conjugation:
PerCP
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
Q9QXH4
Gene ID:
16411
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.