The Anti-Mouse CD11c Antibody (N418) from AssayGenie (Catalog No: AGEL3170) is a highly specific and reliable tool for research related to mouse CD11c, a key marker of dendritic cells. This monoclonal antibody, derived from the N418 hybridoma, is optimized for use in various experimental applications, including flow cytometry, immunofluorescence, and Western blotting.CD11c, also known as integrin alpha X, is a well-established marker for dendritic cells, playing a crucial role in antigen presentation and immune responses. The Anti-Mouse CD11c Antibody (N418) specifically targets this surface molecule, allowing for the precise detection and analysis of CD11c-expressing cells in mouse samples.
This antibody's high specificity and affinity make it an invaluable tool for immunology research, particularly in studies involving dendritic cell biology, inflammation, and host defense mechanisms.By utilizing the Anti-Mouse CD11c Antibody (N418), researchers can gain valuable insights into the function and behavior of dendritic cells in various physiological and pathological conditions. With its proven reliability and versatility in different experimental techniques, this antibody is an essential component for advancing our understanding of immune responses and developing targeted therapies for immune-related disorders.
Product Title:
PerCP Anti-Mouse CD11c Antibody [N418]
SKU:
AGEL3170
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
N418
Synonyms:
Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Form:
Liquid
Conjugation:
PerCP
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
Q9QXH4
Gene ID:
16411
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.