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PerCP Anti-Human CD47 Antibody [CC2C6D4] (AGEL3217)

SKU:
AGEL3217
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Host Species:
Mouse
Isotype:
Mouse IgG1, k
Clone:
CC2C6D4
Conjugation:
PerCP
€279 - €939

Description

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PerCP Anti-Human CD47 Antibody [CC2C6D4]

The perCP Anti-Human CD47 Antibody (CC2C6D4) from Assaygenie targets the CD47 protein, a cell surface molecule with key roles in immune regulation and recognition. This monoclonal antibody is specifically engineered for detecting and analyzing CD47 in human samples, offering a valuable tool for researchers in immunology, cancer biology, and related fields.CD47, also known as integrin-associated protein, is a widely studied molecule due to its involvement in diverse cellular processes, including immune evasion and signal transduction. By targeting CD47 with this perCP-conjugated antibody, researchers can study its expression patterns and functions in various cell types, aiding in the investigation of immune response mechanisms, cancer progression, and potential therapeutic interventions.

The perCP Anti-Human CD47 Antibody (CC2C6D4) is ideal for flow cytometry applications, allowing for precise and sensitive detection of CD47 expression levels on cell surfaces. Its high specificity and reactivity make it a reliable tool for elucidating the roles of CD47 in disease pathogenesis and immune system regulation. Trust in Assaygenie's validated antibody to enhance your research and contribute to a deeper understanding of CD47 biology.

Product Title:PerCP Anti-Human CD47 Antibody [CC2C6D4]
SKU:AGEL3217
Size:20 Tests, 100 Tests, 200 Tests
Clone No:CC2C6D4
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PerCP Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q08722
Gene ID:961
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47 also known as Rh-associated protein, gp42, integrin-associated protein (IAP), and neurophilin, is a 42-52 kD member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. Two splice variants have been described in the cytoplasmic tail, the shorter form is expressed in bone-marrow-derived cells, endothelial cells, and fibroblasts while the longer form is expressed by neural tissues. CD47 expression is widely distributed in hematopoietic cells including thymocytes, T cells, B cells, monocytes, platelets, and erythrocytes as well as epithelial cells, endothelial cells, fibroblasts, and neural tissues. CD47 functions as an adhesion molecule and thrombospondin receptor and is non-covalently associated with β3 integrins CD51/CD61, CD41/CD61. Thrombospondin is a ligand for CD47; in the absence of CD47 mice show defects in host defense and β3 integrin-dependent ligand binding, migration, and cellular activation. CD47 is also part of the Rh complex on erythrocytes.

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