The Anti-Human CD38 Antibody (HIT2) offered by Assay Genie is a vital tool for researchers studying CD38, a transmembrane glycoprotein involved in various cellular processes, including immune regulation and cell signaling. This monoclonal antibody, optimized for use in immunohistochemistry and flow cytometry analyses, specifically targets the CD38 protein on human cells, enabling precise detection and quantification.CD38 is a multifunctional protein expressed on various immune cell types and has been implicated in immune responses, cell adhesion, and calcium signaling. Its dysregulation has been associated with autoimmune diseases, inflammatory conditions, and cancer, highlighting its importance as a potential therapeutic target.
The HIT2 antibody's high specificity and sensitivity make it an invaluable tool for investigating the role of CD38 in health and disease, providing researchers with valuable insights into immune system function and potential therapeutic avenues.Whether you are exploring the immunoregulatory functions of CD38, investigating its role in disease pathogenesis, or developing novel treatments targeting this molecule, the Anti-Human CD38 Antibody (HIT2) from Assay Genie is a reliable choice for your research needs. Trust in its proven performance and robust validation to advance your studies in immunology, oncology, and beyond.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P28907
Gene ID:
952
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.