The TS2/16.2.1 Monoclonal Antibody is a powerful tool for researchers studying the CD29 cell surface protein, also known as integrin beta-1. This antibody, sourced from hybridoma cells, is highly specific and reactive to human CD29 samples. Validated for use in flow cytometry and immunofluorescence applications, it allows for precise detection and analysis of CD29 expression in various cell types.CD29 plays a crucial role in cell adhesion and migration, making it a key player in processes such as cell signaling, differentiation, and tissue formation. By targeting CD29, researchers can gain insights into cell behavior, interactions, and potential therapeutic strategies for conditions involving abnormal cell adhesion.
This TS2/16.2.1 Monoclonal Antibody provides researchers with a reliable tool for investigating the functions and roles of CD29 in cellular processes, making it indispensable for studies in cell biology, immunology, and regenerative medicine. Its specificity and sensitivity make it an essential asset for projects aiming to unravel the complexities of integrin beta-1's involvement in various physiological and pathological mechanisms.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P05556
Gene ID:
3688
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD29 is a 130 kD single chain type I glycoprotein also known as integrin β1, VLA-β chain, or gpIIa. It is broadly expressed on a majority of hematopoietic and non-hematopoietic cells, including leukocytes (although at low level on granulocytes), platelets, fibroblasts, endothelial cells, epithelial cells, and mast cells. CD29 is a member of the integrin family. It is non-covalently associated with integrin α1-α6 chains to form VLA-1 to VLA-6 molecules, respectively. Integrins, which include CD29, bind to several cell surface (e.g. VCAM-1, MadCAM-1) and extracellular matrix molecules. CD29 acts as a fibronectin receptor and is involved in a variety of cell-cell and cell-matrix interactions.