The anti-human CD11c Antibody (BU15) offered by Assay Genie is a highly specific and reliable tool for researchers studying the CD11c cell surface marker in human samples. CD11c is primarily expressed on dendritic cells and a subset of macrophages, playing a crucial role in antigen presentation and immune response.This antibody, produced against human CD11c, is validated for various applications including flow cytometry, immunohistochemistry, and immunofluorescence. Its high reactivity and specificity make it ideal for identifying and isolating CD11c-positive cells in different experimental settings.
By utilizing the anti-human CD11c Antibody (BU15), researchers can gain valuable insights into the role of CD11c-expressing cells in immune responses, inflammation, and various disease conditions. This antibody is a valuable tool for investigating dendritic cell function, immune cell subsets, and potential therapeutic targets in immunology and related fields.Choose the anti-human CD11c Antibody (BU15) from Assay Genie for accurate and reproducible results in your research on CD11c-expressing cells and their implications in immunology and disease pathogenesis.
Product Title:
PerCP Anti-Human CD11c Antibody [BU15]
SKU:
AGEL3260
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
BU15
Synonyms:
Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
PerCP Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
PerCP
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P20702
Gene ID:
3687
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.