The PELP1 Rabbit Monoclonal Antibody (CAB9026) is a highly specific antibody designed for research involving the PELP1 protein, a crucial molecule implicated in various cellular processes such as gene transcription, cell proliferation, and tumorigenesis. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications.PELP1, also known as proline, glutamic acid, and leucine-rich protein 1, plays a significant role in hormone signaling pathways and has been linked to hormone-dependent cancers such as breast and prostate cancer.
By targeting the PELP1 protein, researchers can investigate its function and expression levels in different cell types, providing valuable insights into its involvement in cancer progression and hormone-related diseases.With its specificity and sensitivity in detecting PELP1, this monoclonal antibody is a valuable tool for scientists studying hormone signaling pathways, cancer biology, and therapeutic development. Its application in research may lead to a better understanding of PELP1's role in disease pathogenesis and the identification of potential targets for novel treatment strategies.
Product Name:
PELP1 Rabbit Monoclonal Antibody
SKU:
CAB9026
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human PELP1 (Q8IZL8).
Sequence:
EPEP GLLL EVEE PGTE EERG ADTA PTLA PEAL PSQG EVER EGES PAAG PPPQ ELVE EEPS APPT LLEE ETED GSDK VQPP PETP AEEE METE TEAE ALQE K
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:1000
Synonyms:
MNAR; P160; PELP1
Positive Sample:
SW620,MCF7,SKOV3,NIH/3T3,Rat testis
Conjugate:
Unconjugated
Cellular Localization:
Cytoplasm, Nucleus, nucleoplasm.
Calculated MW:
120kDa
Observed MW:
160kDa
This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
27043
Clone Number:
ARC1387
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PELP1 Rabbit mAb (CAB9026) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
