The PELP1 Polyclonal Antibody (CAB3189) is a vital tool for researchers studying the role of the Proline, Glutamic acid, and Leucine-rich protein 1 (PELP1) in various cellular processes. This antibody, produced in rabbits, demonstrates high reactivity with human samples and is validated for use in Western blot applications. By targeting the PELP1 protein, this antibody allows for the detection and analysis of PELP1 expression in different cell types, making it ideal for studies in cancer research and hormone signaling pathways.PELP1, a multifunctional protein involved in gene regulation and cell growth, is known to impact cancer cell proliferation and hormone receptor signaling.
Its significance in these pathways suggests its potential as a therapeutic target for cancer treatment and hormonal disorders. In-depth understanding of PELP1's role in these processes is crucial for the development of targeted therapies and personalized medicine approaches.Overall, the PELP1 Polyclonal Antibody is a valuable tool for researchers aiming to unravel the intricate functions of PELP1 in cellular processes, particularly in the context of cancer biology and hormone-related diseases. Its high specificity and reliability make it a trusted reagent for immunological and molecular studies.
Product Name:
PELP1 Rabbit Polyclonal Antibody
SKU:
CAB3189
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1021-1180 of human PELP1 (NP_055204.3).
This gene encodes a transcription factor which coactivates transcription of estrogen receptor responsive genes and corepresses genes activated by other hormone receptors or sequence-specific transcription factors. Expression of this gene is regulated by both members of the estrogen receptor family. This gene may be involved in the progression of several types of cancer. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
27043
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PELP1 Rabbit pAb (CAB3189) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
