The PELI3 Polyclonal Antibody (CAB9999) is a valuable tool for research involving PELI3, a key protein involved in immune regulation and inflammation. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the PELI3 protein, this antibody allows for the detection and analysis of PELI3 in various cell types, facilitating studies in immunology and inflammatory diseases.PELI3, also known as Pellino E3 ubiquitin protein ligase family member 3, is a crucial regulator of innate immune responses and inflammatory signaling pathways.
Its role in immune cell activation and cytokine production makes it a promising target for research into autoimmune disorders, infectious diseases, and inflammatory conditions. Understanding the function of PELI3 is essential for developing novel therapeutics that modulate immune responses and inflammation in disease settings.Overall, the PELI3 Polyclonal Antibody (CAB9999) offers researchers a reliable tool for investigating the role of PELI3 in immune regulation and inflammation, providing valuable insights for the development of targeted therapies in various disease contexts.
Product Name:
PELI3 Rabbit Polyclonal Antibody
SKU:
CAB9999
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human PELI3 (NP_659502.2).
The protein encoded by this gene is a scaffold protein and an intermediate signaling protein in the innate immune response pathway. The encoded protein helps transmit the immune response signal from Toll-like receptors to IRAK1/TRAF6 complexes. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
246330
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PELI3 Antibody (CAB9999) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
