The PELI1 Polyclonal Antibody (CAB8240) is a valuable tool for researchers studying the PELI1 protein, a key player in the regulation of immune responses and inflammation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PELI1 protein, this antibody enables precise detection and analysis in a variety of cell types, making it well-suited for investigations in immunology and inflammatory disease research.PELI1, an E3 ubiquitin ligase and essential component of the NF-κB signaling pathway, is involved in controlling immune signaling and cytokine production.
Dysregulation of PELI1 has been linked to various autoimmune disorders, infections, and inflammatory conditions. Therefore, further exploration of its functions and mechanisms is crucial for developing targeted therapies and understanding the complexities of immune system regulation.Overall, the PELI1 Polyclonal Antibody is a valuable tool for researchers aiming to uncover the role of PELI1 in immune response modulation and its potential as a therapeutic target in various disease contexts.
Product Name:
PELI1 Rabbit Polyclonal Antibody
SKU:
CAB8240
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PELI1 (NP_065702.2).
Enables ubiquitin protein ligase activity. Involved in several processes, including negative regulation of necroptotic process; protein polyubiquitination; and response to lipopolysaccharide. Predicted to be located in cytosol.
Purification Method:
Affinity purification
Gene ID:
57162
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of rat brain, using PELI1 antibody (CAB8240) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
