PEG3 Rabbit Polyclonal Antibody (CAB12671)
- SKU:
- CAB12671
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Description
Product Name: | PEG3 Rabbit Polyclonal Antibody |
SKU: | CAB12671 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 195-400 of human PEG3 (NP_006201.1). |
Sequence: | LSLP VVAK TSFE MDRE DDRD SRAY ESRS QDAE SYQN VVDL AEDR KPHN TIQD NMEN YRKL LSLV QLAE DDGH SHMT QGHS SRSK RSAY PSTS RGLK TMPE AKKS THRR GICE DESS HGVI MEKF IKDV SRSS KSGR ARES SDRS QRFP RMSD DNWK DISL NKRE SVIQ QRVY EGNA FRGG FRFN STLV SRKR VLER KRRY HFDT DG |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | PW1; ZNF904; ZSCAN24; ZKSCAN22; PEG3 |
Positive Sample: | HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 181kDa |
Observed MW: | 181kDa |
In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.
Purification Method: | Affinity purification |
Gene ID: | 5178 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |