CD31/PECAM1 Polyclonal Antibody (CAB3181)
- SKU:
- CAB3181
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | CD31/PECAM1 Polyclonal Antibody |
SKU: | CAB3181 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 630-738 of CD31/PECAM1 (NP_000433.4). |
Sequence: | AKQM PVEM SRPA VPLL NSNN EKMS DPNM EANS HYGH NDDV RNHA MKPI NDNK EPLN SDVQ YTEV QVSS AESH KDLG KKDT ETVY SEVR KAVP DAVE SRYS RTEG SLDG T |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | Cd31; Pecam; PECAM-1; CD31/PECAM1 |
Positive Sample: | U-937 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell junction, Cell membrane, Lipid-anchor, Single-pass type I membrane protein. |
Calculated MW: | 81kDa |
Observed MW: | 130kDa |
Predicted to enable protein homodimerization activity; protein phosphatase binding activity; and transmembrane signaling receptor activity. Acts upstream of or within several processes, including Rho protein signal transduction; endothelial cell morphogenesis; and positive regulation of tyrosine phosphorylation of STAT protein. Located in several cellular components, including cell-cell contact zone; external side of plasma membrane; and smooth muscle contractile fiber. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in coronary artery disease (multiple); lung non-small cell carcinoma; neuroblastoma; and psoriatic arthritis. Orthologous to human PECAM1 (platelet and endothelial cell adhesion molecule 1).
Purification Method: | Affinity purification |
Gene ID: | 18613 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |