The PECAM1 Polyclonal Antibody (CAB11525) is a valuable tool for researchers studying PECAM1, also known as platelet endothelial cell adhesion molecule-1. This cell surface receptor is involved in various biological processes, including leukocyte migration and angiogenesis.Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications. By binding to the PECAM1 protein, researchers can accurately detect and analyze its expression in different cell types, providing insights into its role in immune cell interactions and vascular biology.
PECAM1 is known for its crucial role in regulating immune cell trafficking and vascular permeability, making it a key player in inflammatory responses and vascular homeostasis. Research into PECAM1 function is essential for understanding its implications in diseases such as atherosclerosis, inflammation, and cancer progression.By utilizing the PECAM1 Polyclonal Antibody (CAB11525), researchers can gain valuable insights into the mechanisms behind PECAM1-mediated processes, paving the way for potential therapeutic interventions targeting this molecule in various disease contexts.
Product Name:
CD31/PECAM1 Rabbit Polyclonal Antibody
SKU:
CAB11525
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 20-255 of human CD31/PECAM (NP_000433.4).
Cell junction, Cell junction, Cell membrane, Lipid-anchor, Single-pass type I membrane protein.
Calculated MW:
83kDa
Observed MW:
130kDa
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Purification Method:
Affinity purification
Gene ID:
5175
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CD31/PECAM1 Rabbit pAb (CAB11525) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
