The PEBP1 Rabbit Monoclonal Antibody is a highly specific tool for researchers studying the PEBP1 protein, which is involved in various cellular processes including cell survival, proliferation, and migration. This antibody is raised in rabbits and has been extensively validated for its use in immunohistochemistry, immunofluorescence, and Western blot applications.PEBP1, also known as phosphatidylethanolamine-binding protein 1, is a multifunctional protein that interacts with numerous signaling pathways and is implicated in cancer progression, neuronal function, and cell growth regulation. The availability of a reliable antibody for PEBP1 detection allows for precise localization and quantification of the protein in different cell types and tissue samples.
Research into the role of PEBP1 in various diseases, such as cancer and neurological disorders, has highlighted its potential as a therapeutic target. By understanding the mechanisms by which PEBP1 influences key cell signaling pathways, researchers can develop novel strategies for intervention and treatment. The PEBP1 Rabbit Monoclonal Antibody is a valuable tool for advancing our understanding of PEBP1 function and its implications in disease pathology.
Product Name:
PEBP1 Rabbit Monoclonal Antibody
SKU:
CAB12768
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PEBP1 (P30086).
This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome.
Purification Method:
Affinity purification
Gene ID:
5037
Clone Number:
ARC0704
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PEBP1 Rabbit mAb (CAB12768) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
