The PEA15 Polyclonal Antibody (CAB9956) is a valuable tool for researchers studying the protein PEA15, which is involved in regulating cell survival, proliferation, and apoptosis. This antibody, generated in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By binding to the PEA15 protein, this antibody allows for precise detection and analysis in a variety of cell types, making it an essential component for studies in cell biology and cancer research.PEA15, also known as phosphoprotein enriched in astrocytes 15 kDa, is a critical regulator of pathways that control cell growth and survival. Its importance in these processes makes it a promising target for research into diseases such as cancer, where abnormal cell proliferation and survival are key characteristics.
By studying PEA15 and its functions, researchers can gain valuable insights into the mechanisms underlying disease progression and potentially identify new therapeutic targets for intervention.Overall, the PEA15 Polyclonal Antibody (CAB9956) is a reliable tool for investigating the role of PEA15 in various cellular processes and disease states. Its high specificity and sensitivity make it an indispensable resource for researchers looking to advance our understanding of cell signaling pathways and potentially develop novel treatments for cancer and other related disorders.
Product Name:
PEA15 Rabbit Polyclonal Antibody
SKU:
CAB9956
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human PEA15 (NP_003759.1).
This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8682
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PEA15 antibody (CAB9956) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
