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PE-Labeled Recombinant Human ERBB1/HER1/EGFR (25-378) Protein (RPCB0558)

SKU:
RPCB0558
Size:
100µg
Tag:
C-His&Avi
Reactivity:
Human
€1,329

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:PE-Labeled Recombinant Human ERBB1/HER1/EGFR (25-378) Protein
SKU:RPCB0558
Size:100µg
Tag:C-His&Avi
Reactivity:Human
Protein Description:High quality, high purity and low endotoxin recombinant PE-Labeled Recombinant Human HER1/ERBB1/EGFR (25-378) Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 1 EU/μg of the protein by LAL method
Formulation:Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Gene ID:1956

The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.

Storage:Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Swiss-Prot:NP_001333870.1
Product ImageFACS Analysis of Anti-EGFRVIII CAR Expression. 293T cells were transfected with anti-EGFRVIII-scFv and His tag. Cells were incubated with 5 μg/mL PE-Labeled Human EGFRVIII, His Tag and PE-labeled protein control. Non-transfected 293T cells and PE-labeled protein control were used as negative control.

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