The PE GenieFluor 594 Anti-Rat CD3 Antibody (G4.18) (AGEL3033) is a highly specific and sensitive tool for detecting CD3 expression in rat samples. CD3 is a crucial T-cell co-receptor involved in cellular immune response and is widely used as a marker for T cells. This antibody, raised in rats, offers high reactivity and specificity for CD3, making it an ideal choice for flow cytometry and immunofluorescence applications in research settings.In studies involving T-cell biology, immunology, and immune system function, the ability to accurately detect and quantify CD3 expression is essential.
The PE GenieFluor 594 Anti-Rat CD3 Antibody (G4.18) provides reliable and consistent results for researchers looking to investigate T-cell activation, differentiation, and function in various experimental models. With its robust performance and versatility, this antibody is a valuable tool for advancing our understanding of immune responses and evaluating potential therapeutic interventions in immune-related diseases.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P19377 Q64159 D4A5M2
Gene ID:
25710,300678,315609,25300
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3 is a complex composed of δ, γ, ε, and ζ chains. They are 20-25 kD members of the immunoglobulin superfamily and associated with the T cell receptor (TCR). CD3 is expressed on thymocytes, peripheral T cells, some NK-T cells, and dendritic epidermal T cells. CD3 is involved in antigen recognition, signal transduction, and T cell activation.