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PE/GenieFluor 594 Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL3234)

SKU:
AGEL3234
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
Rat IgG2b, k
Clone:
M1/70
Conjugation:
PE/AF594
€109 - €249
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Mouse/Human CD11b Antibody [M1/70]

The PE GennieFluor 594 Anti-Mouse/Human CD11b Antibody (M1/70) is a valuable tool for researchers investigating the CD11b protein, a key cell surface marker involved in immune cell function. This antibody, specifically designed for use with mouse and human samples, is highly specific and ideal for flow cytometry applications. By targeting the CD11b protein, this antibody enables precise detection and analysis in a variety of cell types, providing crucial insights into immune responses and inflammatory processes.CD11b, also known as integrin alpha M, is a well-known marker of myeloid cells such as monocytes, macrophages, and neutrophils. Its role in mediating adhesion and migration of immune cells makes it a pivotal player in the immune system's response to infection, inflammation, and tissue repair.

Researchers studying immunology, inflammation, and infectious diseases will benefit from the accurate identification and quantification of CD11b-expressing cells facilitated by this antibody.By using the PE GennieFluor 594 Anti-Mouse/Human CD11b Antibody (M1/70), scientists can gain deeper insights into the role of CD11b in immune cell function and its implications for health and disease. This antibody's high specificity, sensitivity, and compatibility with flow cytometry make it a valuable asset for research projects seeking to understand the intricate mechanisms of immune cell activation and regulation.

Product Title:PE/GenieFluor 594 Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL3234
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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