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PE/GenieFluor 594 Anti-Mouse CD86 Antibody [GL-1] (AGEL3176)

SKU:
AGEL3176
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
GL-1
Conjugation:
PE/AF594
€189 - €489
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Mouse CD86 Antibody [GL-1]

The PE GenieFluor 594 Anti-Mouse CD86 Antibody (GL-1) is a highly specialized tool for researchers investigating CD86, a crucial co-stimulatory molecule involved in immune responses. This antibody, optimized for use in flow cytometry applications, is specifically designed for detection and analysis of CD86 expression on mouse cells. With its high reactivity and specificity, the PE GenieFluor 594 Anti-Mouse CD86 Antibody (GL-1) is an invaluable asset for immunologists and researchers studying immune regulation, autoimmune diseases, and inflammatory conditions in mouse models.

CD86, also known as B7-2, plays a pivotal role in T cell activation and is essential for effective immune responses. Its dynamic expression patterns and interactions with T cells make it a key target for understanding immune modulation and developing therapeutic interventions. By enabling precise detection and measurement of CD86 levels, the PE GenieFluor 594 Anti-Mouse CD86 Antibody (GL-1) empowers researchers to unravel the complexities of immune signaling pathways and explore novel strategies for immune system manipulation.

Product Title:PE/GenieFluor 594 Anti-Mouse CD86 Antibody [GL-1]
SKU:AGEL3176
Size:25µg, 100µg
Clone No:GL-1
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P42082
Gene ID:12524
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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