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PE/GenieFluor 594 Anti-Mouse CD86 Antibody [GL-1] (AGEL3175)

SKU:
AGEL3175
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
GL-1
Conjugation:
PE/AF594
€249 - €569
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Mouse CD86 Antibody [GL-1]

The PE-GenieFluor 594 Anti-Mouse CD86 Antibody (GL-1) is a specialized antibody designed for research applications involving the CD86 protein in mouse models. CD86 is a crucial cell surface molecule involved in immune responses, particularly in the activation of T cells and modulation of immune signaling pathways. The GL-1 antibody, optimized for use in flow cytometry and immunofluorescence studies, specifically targets and binds to mouse CD86, enabling precise detection and analysis in various biological samples.With its high specificity and sensitivity, the PE-GenieFluor 594 Anti-Mouse CD86 Antibody (GL-1) offers researchers a valuable tool for investigating the role of CD86 in immune regulation, inflammation, and autoimmune diseases.

By accurately identifying and quantifying CD86 expression, this antibody facilitates the study of immune cell interactions, antigen presentation, and the development of immune-based therapies. Whether exploring basic immunology mechanisms or developing novel treatment strategies, this antibody serves as a reliable and effective tool for advancing research in the field of immunology.

Product Title:PE/GenieFluor 594 Anti-Mouse CD86 Antibody [GL-1]
SKU:AGEL3175
Size:50 Tests, 100 Tests, 200 Tests
Clone No:GL-1
Synonyms:T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P42082
Gene ID:12524
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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