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PE/GenieFluor 594 Anti-Mouse CD80 Antibody [16-10A1] (AGEL3172)

SKU:
AGEL3172
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
16-10A1
Conjugation:
PE/AF594
€249 - €569
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Mouse CD80 Antibody [16-10A1]

The PE-GenieFluor 594 Anti-Mouse CD80 Antibody (16-10A1) from AssayGenie (AGEL3172) is a high-quality antibody designed for researchers studying immune responses and cell signaling pathways in mice. This antibody specifically targets CD80, a critical co-stimulatory molecule expressed on antigen-presenting cells that plays a key role in T cell activation and immune response regulation.Produced using advanced technology, this antibody is highly specific and provides reliable results in various experimental applications such as flow cytometry, immunofluorescence, and immunohistochemistry. Its bright PE-GenieFluor 594 conjugate allows for easy visualization and quantification of CD80 expression in mouse tissues and cells.

By using the PE-GenieFluor 594 Anti-Mouse CD80 Antibody (16-10A1), researchers can gain valuable insights into the function of CD80 in immune responses, inflammation, and autoimmune diseases. This antibody is a valuable tool for advancing research in immunology, cancer immunotherapy, and other fields where understanding CD80 signaling is essential for developing targeted therapies.Ensure the success of your experiments with the high-performance PE-GenieFluor 594 Anti-Mouse CD80 Antibody (16-10A1) from AssayGenie.

Product Title:PE/GenieFluor 594 Anti-Mouse CD80 Antibody [16-10A1]
SKU:AGEL3172
Size:50 Tests, 100 Tests, 200 Tests
Clone No:16-10A1
Synonyms:T-lymphocyte activation antigen CD80;Cd80;Activation B7-1 antigen;B7;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:PE/Genie Fluor 594 Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q00609
Gene ID:12519
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

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