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PE/GenieFluor 594 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL3242)

SKU:
AGEL3242
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
R17 217.1.3/TIB-219
Conjugation:
PE/AF594
$263 - $623
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The PE GenieFluor 594 Anti-Mouse CD71 Antibody (R17-217.1.3/TIB-219) is a powerful tool for researchers studying mouse CD71, a transferrin receptor involved in cellular iron uptake and metabolism. This antibody, conjugated with PE GenieFluor 594 for fluorescent detection, offers high specificity and sensitivity in various applications such as flow cytometry and immunofluorescence.CD71, also known as transferrin receptor protein 1, plays a crucial role in iron homeostasis by mediating the internalization of transferrin-bound iron into cells. Its expression is often upregulated in rapidly dividing cells, making it a valuable marker for cell proliferation and as a target for cancer therapy research.

The PE GenieFluor 594 Anti-Mouse CD71 Antibody enables precise detection and analysis of CD71 expression, facilitating detailed investigations in areas like oncology, cell biology, and immunology.This antibody is a reliable tool for researchers aiming to elucidate the role of CD71 in various physiological and pathological processes, including iron metabolism disorders, cancer progression, and immune responses. Its outstanding performance and versatility make it an essential component for studies seeking to uncover the mechanisms underlying CD71 function and its potential implications for therapeutic development.

Product Title:PE/GenieFluor 594 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL3242
Size:25µg, 100µg
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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