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PE/GenieFluor 594 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219] (AGEL3240)

SKU:
AGEL3240
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
R17 217.1.3/TIB-219
Conjugation:
PE/AF594
€279 - €639

Description

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PE/GenieFluor 594 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]

The PE GenieFluor 594 Anti-Mouse CD71 Antibody (R17-217-1-3-TIB-219) from Assay Genie is a highly specific antibody designed for the detection of CD71, also known as the transferrin receptor, in mouse samples. This antibody, validated for use in flow cytometry applications, binds specifically to CD71, enabling accurate detection and analysis in various cell types.CD71 is a cell surface receptor involved in the uptake of iron-bound transferrin, playing a crucial role in iron homeostasis and cell proliferation. Its overexpression is often associated with increased iron demand in actively proliferating cells, making it a valuable marker in cancer research and studies on cellular proliferation.

By targeting CD71 in mouse samples, researchers can gain insights into iron metabolism, cell proliferation, and potential therapeutic targets in cancer and other diseases. With its high specificity and sensitivity, the PE GenieFluor 594 Anti-Mouse CD71 Antibody is an essential tool for elucidating the role of CD71 in various biological processes.

Product Title:PE/GenieFluor 594 Anti-Mouse CD71 Antibody [R17 217.1.3/TIB-219]
SKU:AGEL3240
Size:50 Tests, 100 Tests, 200 Tests
Clone No:R17 217.1.3/TIB-219
Synonyms:Transferrin receptor protein 1;Tfrc;TR;TfR;TfR1;Trfr;CD71;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q62351
Gene ID:22042
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD71 is a 95 kD type II heterodimeric transmembrane glycoprotein that is also known as T9 and transferrin receptor. CD71 is expressed on proliferating cells, reticulocytes, and erythroid precursors. Its expression is very low on resting leukocytes. CD71 plays a role in the control of cellular proliferation by facilitating the uptake of iron via ferrotransferrin binding and the recycling of apotransferrin to the cell surface.

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