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PE/GenieFluor 594 Anti-Mouse CD40 Antibody [FGK4.5/FGK45] (AGEL3187)

SKU:
AGEL3187
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
FGK4.5/FGK45
Conjugation:
PE/AF594
$311 - $731
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]

The PE GenieFluorâ„¢ 594 Anti-Mouse CD40 Antibody (FGK4.5) is a specialized tool designed for precise and reliable detection of CD40, a crucial cell surface receptor involved in immune responses and inflammation. This antibody, generated for use in mouse samples, is specifically tailored for flow cytometry applications, allowing for high-resolution analysis of CD40 expression on various immune cell populations.CD40, a member of the tumor necrosis factor receptor superfamily, plays a pivotal role in regulating immune activation, antigen presentation, and antibody production. Its diverse functions in modulating immune signaling pathways make it a key target for research in immunology, vaccine development, and autoimmune diseases.

By accurately detecting and quantifying CD40 expression in mouse cells, this antibody facilitates in-depth investigations into the mechanisms underlying immune responses and the development of novel therapeutic strategies targeting CD40-mediated pathways.With its superior performance in flow cytometry experiments, the PE GenieFluorâ„¢ 594 Anti-Mouse CD40 Antibody (FGK4.5) offers researchers a valuable tool for unraveling the complexities of immune regulation and advancing insights into immune-related disorders. Trust in this antibody for robust and reproducible results in your studies of CD40 biology and its implications for diverse areas of immunological research.

Product Title:PE/GenieFluor 594 Anti-Mouse CD40 Antibody [FGK4.5/FGK45]
SKU:AGEL3187
Size:50 Tests, 100 Tests, 200 Tests
Clone No:FGK4.5/FGK45
Synonyms:Tumor necrosis factor receptor superfamily member 5;Cd40;B-cell surface antigen CD40;Bp50;CD40L receptor;CD40;Tnfrsf5;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27512
Gene ID:21939
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

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