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PE/GenieFluor 594 Anti-Mouse CD335 Antibody [29A1.4] (AGEL3275)

SKU:
AGEL3275
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Reactivity:
Mouse
Host Species:
Rat
Isotype:
Rat IgG2a, k
Clone:
29A1.4
Conjugation:
PE/AF594
€259 - €609
Frequently bought together:

Description

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PE/GenieFluor 594 Anti-Mouse CD335 Antibody [29A1.4]

The PE-GeneFluor 594 Anti-Mouse CD335 Antibody (29A1.4) is a highly specific and sensitive tool designed for the detection and analysis of CD335, a cell surface receptor involved in natural killer (NK) cell function. This antibody, developed for use in mouse samples, is validated for various applications, including flow cytometry and immunofluorescence.CD335, also known as NKp46, is a key receptor expressed on NK cells that plays a crucial role in recognizing and killing target cells, particularly infected or tumor cells.

Understanding the expression and activation of CD335 is essential for unraveling the mechanisms of NK cell activity in immunity and disease. This antibody enables researchers to study the distribution and function of CD335 in different cell populations, providing valuable insights into the role of NK cells in immune responses and therapeutic interventions.

Product Title:PE/GenieFluor 594 Anti-Mouse CD335 Antibody [29A1.4]
SKU:AGEL3275
Size:25µg, 100µg
Clone No:29A1.4
Synonyms:Ly94;mAR-1;NK-p46;mNKp46;Lymphocyte antigen 94;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2a, κ
Isotype Control:PE/Genie Fluor 594 Rat IgG2a, κ Isotype Control[2A3]
Form:Liquid
Conjugation:PE/Genie Fluor594
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q8C567
Gene ID:17086
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD335, also known as NKp46, is a single-pass type I membrane protein of 46 kD. It belongs to the natural cytotoxicity receptor (NCR) family and contains two Ig-like (immunoglobulin-like) domains. It's expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. CD335 is a receptor for viral hemagglutinins and heparan sulfate proteoglycans and is involved in NK cell activation.

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