The PE GenieFluor 594 anti-Mouse CD3 Antibody (17A2) (AGEL3183) is a high-quality antibody designed for research involving the CD3 antigen, a crucial T cell co-receptor involved in immune response activation. This antibody, specifically targeting mouse CD3 antigen, is highly reactive and suitable for use in various immunological studies.Raised in rabbits, this antibody is validated for use in flow cytometry applications, enabling the detection and analysis of CD3 expression in mouse cell samples. Its specificity for the CD3 antigen makes it an essential tool for investigating T cell activation, differentiation, and function, particularly in studies related to immunology, infectious diseases, and autoimmune disorders.
The PE-conjugated GenieFluor 594 visualization marker provides bright and stable fluorescence, allowing for easy and accurate assessment of CD3 expression levels. With its reliability and performance in flow cytometry, the PE GenieFluor 594 anti-Mouse CD3 Antibody (17A2) (AGEL3183) is a valuable asset for researchers studying T cell biology and immunological processes in mouse models.
Product Title:
PE/GenieFluor 594 Anti-Mouse CD3 Antibody [17A2]
SKU:
AGEL3183
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
17A2
Synonyms:
T-cell surface glycoprotein CD 3epsilon/delta/gamma/zeta chain;CD3E/D/G/Z;CD3e/d/g/z;CD3E/D/G/Z;CD3;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Genie Fluor 594 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Genie Fluor594
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04235 P11942 P22646 P24161
Gene ID:
12502
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.