The PE-GenieFluor 594 Anti-Mouse CD16/32 Antibody (2.4G2) (AGEL3179) is a highly specific antibody designed for research involving the CD16/32 cell surface molecules in mice. These molecules are important for immune regulation, particularly in the activation of immune responses. The antibody, raised in rabbits, is validated for use in flow cytometry applications and binds specifically to CD16/32 proteins, allowing for accurate detection and analysis in various cell types.
This antibody is ideal for studies in immunology and cancer research, as understanding the role of CD16/32 in immune response modulation is crucial for developing targeted therapies for diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
CD16a/b;CD32;CD32A/B;Fc fragment of IgG low affinity IIa/b receptor;Fc fragment of IgG low affinity IIIa/b receptor;Fc fragment of IgG low affinity IIIb receptor;Fc gamma receptor III A/B;FCG2A;FcGR;FCGR2A/BFCGR3;FCGR3A/B;Fc gamma RIIa/b ;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Genie Fluor 594 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Genie Fluor594
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P08508 P08101
Gene ID:
14130,14131
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD16 is low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses.