The PE GenieFluor 594 Anti-Mouse CD11a Antibody (FD441-8) is a highly specific and sensitive tool for researchers studying CD11a, a critical cell adhesion molecule involved in immune responses. This antibody, developed for use in flow cytometry applications, is ideal for detecting and analyzing CD11a expression on mouse cells.CD11a, also known as integrin alpha L, plays a key role in T cell activation and trafficking, making it a crucial target for studies in immunology and inflammation. The PE GenieFluor 594 Anti-Mouse CD11a Antibody is validated for use in flow cytometry experiments, allowing for precise and accurate detection of CD11a-positive cells in various mouse tissues and cell types.
Researchers investigating T cell function, immune cell interactions, and inflammatory processes will benefit from the specificity and reliability of this antibody. With its high reactivity and sensitivity, the PE GenieFluor 594 Anti-Mouse CD11a Antibody is a valuable tool for advancing research in immunology, autoimmune diseases, and inflammatory conditions.
Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Genie Fluor 594 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Genie Fluor594
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P24063
Gene ID:
16408
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).